What is Mammalian Meat Allergy?
Understanding Mammalian Meat Allergy Triggered by Tick Bites
While there are many triggers of anaphylaxis, one of the more unusual is mammalian meat allergy.
This allergy develops after a person has been bitten by a tick. These patients may become allergic to all mammalian meat - beef, pork, lamb, kangaroo, and also allergic to meat products, including dairy and anything containing gelatine, glycerine or substances which include traces of animal by-products such as toothpaste, moisturisers and wine. There have been cases of people developing mammalian meat allergy after tick bites and it may manifest as anaphylaxis up to 12+ hrs after ingestion.
Alpha-gal: The Culprit Behind Mammalian Meat Allergy
This allergy is produced by a reaction to Alpha-gal (galactose-alpha-1,3-galactose) which is a carbohydrate found in the blood of all mammals except for humans and the great apes. When ticks bite a mammal such as a bandicoot, possum or rat, they pick up the alpha-gal, and then it is transferred to humans via the tick bite.
If you would like to know more about anaphylaxis, envenomation and more, consider:
- The ALERT Course (Acute Life-threatening Emergencies Recognition and Treatment)
- Responding to Anaphylaxis - Minutes Matter
- Emergencies in General Practice
Article last reviewed September 2023 by Susie Helmrich.
References:
Jackson WL. 2018. Mammalian meat allergy following a tick bite: a case report. Oxf Med Case Reports. 2018 Feb; 2018(2): omx098. Published online 2018 Feb 21. doi: 10.1093/omcr/omx098. PMCID: PMC5822700. PMID: 29492269.
van Nunen SA. 2018. Tick-induced allergies: mammalian meat allergy and tick anaphylaxis. Med J Aust; 208 (7): 316-321. doi: 10.5694/mja17.00591. Published online: 16 April 2018
Ken Hambrecht RN, ICU Cert., B.Sc, (Physiology & Biochem.), M.I.Biol, M.Ed., J.P. MACN, has extensive experience in Critical Care practice & Medical education. This includes more than 25 years co-ordinating & teaching Critical Care Courses and other Medical Education. Ken is the Founder and Principal Consultant for Critical Care Education Services.
In recognition of his outstanding contribution to medical education, Ken has been awarded honorary life membership of the Australian College of Perianaesthesia Nurses (ACPAN). Ken has also been a member of the Australian Resuscitation Council, including the Advanced Life Support Committee.
Become a member and get unlimited access to 100s of hours of premium education.
Learn moreThis article explores the risks and management of dynamic hyperinflation in mechanically ventilated patients with status asthmaticus. It outlines causes such as airway obstruction and bronchospasm, and provides strategies for adjusting ventilation settings to minimise gas trapping, support cardiac function, and reduce complications like pneumothorax and systemic hypotension.
While cardiac arrest is often a rare event, the high stakes nature means we need to be able to respond instinctively, ensuring immediate effective action when it matters most. How do you stay prepared in-between ALS or PALS courses?
Nutrition plays a vital role in the recovery of critically ill patients. Evidence-based recommendations for patients in the ICU focus on the timing, energy requirement and protein targets as well as the role of micronutrients. The route of administration is not always straightforward and best guided by the patient's clinical needs, indications and contraindications.