Recurrent miscarriage, also referred to as recurrent pregnancy loss (RPL), is defined as the loss of two or more confirmed intrauterine pregnancies of up to 20 weeks’ gestation. This definition includes both consecutive and non-consecutive losses, provided each loss is confirmed. RPL affects approximately 1–4% of couples, with the risk increasing with maternal age. Though the causes remain unexplained in up to 50% of cases, a range of anatomical, genetic, endocrine, immunological and thrombophilic factors may be implicated. Each pregnancy loss can have significant psychological and emotional consequences, underlining the importance of compassionate and comprehensive care in general practice.
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